Education

Concepts of Organic Synthesis (CY5L003); Organic chemistry Lab. (CY5P001); Organic Spectroscopy (CY5L028); Advanced Organic Chemistry (CY5L007);

1. Total Synthesis of (’)-Magnoshinin and (+)-Merrilliaquinone: Application of a Late-Stage Oxidative Functionalization Protocol; Abdus Salam, Dileep Kumar, Tonish Kumar Sahu, Rahimuddin Khan and Tabrez Khan, Eur. J. Org. Chem. 2022 (Just Accepted) https://doi.org/10.1002/ejoc.202101452
2. DDQ-Catalyzed Oxidative C(sp3)”H Functionalization of Aryltetralins and Subsequent Chemoselective Oxidative Demethylation to Access Dihydronaphthalenes and Dihydronaphthoquinones; Dileep Kumar, Abdus Salam, Tonish Kumar Sahu, Sujit Soumitra Sahoo and Tabrez Khan, J. Org. Chem. 2021, 86, 15096-15116.
3. Concise and Scalable Total Syntheses of Lamellarin Z and other Natural Lamellarins; Virendra Kumar, Abdus Salam, Dileep Kumar and Tabrez Khan, ChemistrySelect 2020, 5, 14510-14514.
4. A silica-gel accelerated [4+2] cycloaddition-based biomimetic approach towards the first total synthesis of magterpenoid C; Dileep Kumar, Virendra Kumar, Abdus Salam and Tabrez Khan, Tetrahedron Lett. 2019, 60, Article 151137
5. Scalable Total Syntheses of some Natural and Unnatural Lamellarins: Application of a One-Pot Domino process for Regioselective Access to the Central 1,2,4-Trisubstituted Pyrrole Core; Virendra Kumar, Annapurna Awasthi, Abdus Salam and Tabrez Khan, J. Org. Chem. 2019, 84, 11596-11603.
6. A Metal Free Domino Process for Regioselective Synthesis of 1,2,4-Trisubstituted Pyrroles: Application towards the Formal Synthesis of Ningalin B; Virendra Kumar, Annapurna Awasthi, Abhisek Metya and Tabrez Khan, J. Org. Chem. 2019, 84, 11581-11595.
7. Total Syntheses of several Iridolactones and the Putative Structure of Noriridoid Scholarein A: An Intramolecular Pauson-Khand Reaction based One-stop Synthetic Solution; Abdus Salam, Sayan Ray, Md. Abu Zaid, Dileep Kumar and Tabrez Khan, Org. Biomol. Chem. 2019, 17, 6831-6842.
8. A De Novo Approach for the Stereoselective Synthesis of Cyclopenta[c]pyranone Scaffold Present in Iridoids: Formal Syntheses of Isoboonein, Iridomyrmecin and Isoiridomyrmecin, Manvendra Singh Kaurav, Virendra Kumar, Dileep Kumar and Tabrez Khan, ChemistrySelect, 2018, 3, 5566-5570
9. Synthetic studies en route to the first total synthesis of a naturally occurring quinone from Acorus gramineus, iso-merrilliaquinone, iso-magnoshininand 2-epi-3,4-dihydro magnoshinin; Dileep Kumar, Oindreela Das, Manvendra Singh Kaurav, Tabrez Khan, RSC Advances. 2017, 7, 36844-36851.
10. “An Improved Synthesis of Natural Product Inspired Chromenopyrrolizines and Chromenoindolizines Scaffolds: Rapid Access to the Diverse Pyrrolizine Analogs of Aza-Medicarpin and Tetracyclic Isolamellarin Core through a General Base and Metal free Strategy” Tabrez Khan, Virendra Kumar, Oindreela Das, Bull. Chem. Soc. Jpn. 2016, 89, 1331.
11. “Total Synthesis and Structural Revision of Antibiotic CJ-16,264” K. C. Nicolaou, Akshay A. Shah, Henry Korman, Tabrez Khan, Lei Shi, Wisuttaya Worawalai, Emmanuel A. Theodorakis, Angew.Chem. Int.Ed. 2015, 54,9203 “9208
12. Model studies toward a synthesis of asperaculin A: exploration of iterative intramolecular Pauson”Khand reaction based strategies to access the dioxa[5.5.5.6]fenestrane framework”; Goverdhan Mehta, Tabrez Babu Khan, Tetrahedron Letters, 2012, 53, 4558-4561.
13. “(1-S,6-S,8-S,9-R)-9–Bromo-12–oxaspiro-[1,3-dioxolane-2,4–tricyclo[6.3.1.01,6]- dodecane]”; Goverdhan Mehta, Tabrez Babu Khan, Acta Crystallogr., Sect. E: Struct. Rep. Online, 2012, E68, o2411-o2412.
14. “A biomimetic total synthesis of allomicrophyllone: protective Diels”Alder reaction as a stratagem”; Goverdhan Mehta, Tabrez Babu Khan, Tetrahedron Letters, 2010, 51, 6590-6593.
15. “Total synthesis of the fungal metabolite (±)-acremine G: acceleration of a biomimetic Diels”Alder reaction on silica gel”; Goverdhan Mehta, Tabrez Babu Khan, Y.C. Sunil Kumar, Tetrahedron Letters, 2010, 51, 5116-5119.
16. “Total syntheses of the fungal metabolites (±)-acremines A, B and I”; Goverdhan Mehta, Y.C. Sunil Kumar, Tabrez Babu Khan, Tetrahedron Letters, 2010, 51, 5112- 5115.
17. “Anthracene-tethered aminomethyl oxadiazole chemosensor: a probe offering selective chromo- and fluorogenic signaling for targeting Cu(II)”; Sabir H. Mashraqui, Tabrez Khan, Mukesh Chandiramani, Rupesh Betkar and Kiran Poonia, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2010, 67, 361-367.
18. “Rhodamine”Pyridyl Probe: A Selective Optical Reporter for Biologically Important Zn2+, Sabir H. Mashraqui, Tabrez Khan, Subramanian Sundaram, Rupesh Betkar and Mukesh Chandiramani, Chemistry Letters, 2009, 38, 730-731.
19. “Phenothiazine-pyridyl chalcone: A new easily accessible colorimetric and fluorimetric “on-off ” dual sensing probe for Cu2+”, Sabir H. Mashraqui, Tabrez Khan, Subramanian Sundaram, and Shailesh Ghadigaonkar, Tetrahedron Letters, 2008, 49, 3739-3743.
20. “New PCT probes featuring N-phenylmonoaza-18-crown-6 and aryl/pyridyloxadiazoles: Optical Spectral Studies of Solvent effects and selected metal ions”;Sabir H. Mashraqui, Subramanian Sundaram, Tabrez Khan, Shailesh Ghadigaonkar and Kirandevi Poonia, Journal of Inclusion Phenomenon & Macrocyclic Chemistry, 2008, 62, 81-90.
21. “A new intramolecular charge transfer receptor as a selective ratiometric “off-on” sensor for Zn2+”, Sabir H. Mashraqui, Tabrez Khan, Subramanian Sundaram, Rupesh Betkar and Mukesh Chandiramani, Tetrahedron Letters, 2007, 48, 8487- 8490.
22. “Zn2+ selective luminescent “off-on” probes derived from diaryl oxadiazole and aza- 15-crown-5″; Sabir H. Mashraqui, Subramanian Sundaram, Tabrez Khan and A. C. Bhasikuttan, Tetrahedron, 2007, 63, 11093-11100.
23. “Benzimidazole-Chalcone: A Selective Intramolecular Charge-transfer Probe for Biologically Important Zinc Ions”, Sabir H. Mashraqui, Subramanian Sundaram and Tabrez Khan, Chemistry Letters, 2006, 35, 786-787.

1. Tabrez Khan, Virendra Kumar & Oindreela Das, “A Rapid Access to the Diverse Pyrrolizine Analogs of Aza-Medicarpin and Tetracyclic Isolamellarin Core through a General Base and Metal free Strategy” (ICOS-21), Dec 2017, IIT Bombay, India
2. Tabrez Khan & Oindreela Das, “Synthetic Studies towards some natural product with potent cytotoxicity towards HCC cells” First International Conference on Nutraceuticals & Chronic Diseases (INCD-2016), Sept. 2016, Kerala, India
3. Goverdhan Mehta & Tabrez Khan, “Biomimetically Inspired First Total Synthesis of Allomicrophyllone”, 6th Junior National Organic Symposium trust Conference (J- NOST), 2011, Hyderabad, India.
4. Goverdhan Mehta, Sunil Kumar Y. C., Tabrez Khan, “Total Syntheses of Acremine A, B, I & G”, 5th Junior National Organic Symposium trust Conference (J-NOST), 2009, Kanpur, India.

• Assistant Professor- School of Basic Sciences, IIT Bhubaneswar,  April 2014- Present
• Research Investigator- Medicinal Chemistry at BBRC (Biocon-BMS R&D Centre, Syngene Intl. Ltd), Bangalore,  India, Sept. 2013- April 2014.
• Postdoctoral Researcher with Prof. K. C. Nicolaou at The Scripps Research Institute, CA, USA, 2012-2013.
• Postdoctoral Researcher with Prof. Goverdhan Mehta at Hyderabad Central University, India, 2010-2012.
• Postdoctoral Researcher with Prof. Goverdhan Mehta at Indian Institute of Science, Bangalore, India, 2009-2010.
• Research Associate at GlaxoSmithKline Pharmaceuticals, Maharashtra, India, 2008-2009.
• Doctoral Research at University of Mumbai with Prof. S. H. Mashraqui, Maharashtra, India, 2003-2008