School of Basic Sciences

IIT Bhubaneswar Logo
Department of
Chemistry
School of Basic Sciences

Dr. Tabrez Khan

Associate Professor
  • Office: 220, SBS
  • +91 674 7135164
  • tabrez@iitbbs.ac.in
  • Department of Chemistry
IRINS Profile
Brief Resume
Google Scholar
Personal Website
Research Interests:
1. Heat-/Light-/Electricity-mediated Catalytic/Non-catalytic Synthetic Method Development for Functionalized Heterocycles/Carbocycles synthesis. 2. Greener Synthetic Strategies employing Cycloadditions Strategy, metal- free late-stage C-H functionalization approaches, and other modern methods. 3. Repurposing the existing chemical space for developing new methodologies. 4. Asymmetric Total Synthesis of Bioactive Marine Alkaloids, Terpenoids, and Natural products of mixed biosynthetic origin
Education
 Degree Discipline Year School
  Ph.D. Organic Chemistry 2009 University Of Mumbai
  DSK Postdoctoral Fellow Natural Products Synthesis 2010-2011 Indian Institute of Science Bangalore
  DSK Postdoctoral Fellow Natural Products Synthesis 2011-2012 Hyderabad Central University
  Fulbright-Nehru Postdoctoral Fellow Natural Products Synthesis 2012-2013 The Scripps Research Institute, California

Concepts of Organic Synthesis (CY5L003)

Organic Chemistry Lab. (CY5P001)

Organic Spectroscopy (CY5L028)

Advanced Organic Chemistry (CY5L007)

Organic Reaction Mechanism (ITEP)

Chemistry (B. Tech)

  • Fulbright-Nehru Postdoctoral fellowship from the United States-India Education Foundation (USIEF), New Delhi, India (2012-2013).
  • Dr. D. S. Kothari Postdoctoral fellowship from the University Grants Commission (UGC), New Delhi, India (2009-2012).
  • Best Poster Award at Trombay Symposium for Radiation and Photochemistry from the Department of Atomic Energy, Govt. of India (2008).
  • Best Talk Award at Ph.D Student Symposium from the Royal Society of Chemistry- West India Section (2007).
  • Junior & Senior Research Fellowship Award from the Council of Scientific & Industrial Research (CSIR), New Delhi, India (2004-2008).
  • Graduate Aptitude Test In Engineering (GATE) Award from the Indian Institute of Technology, India (2004).
  • Maharashtra State level Eligibility for Lectureship Award from the University Grants Commission (UGC), New Delhi, India (2003).
  1. DABSO-mediated Pummerer reaction enables onepot synthesis of pyrroloquinolines for accessing marinoquinolines: mechanistic, photophysical and pharmacological investigations  Rahimuddin Khan, Dipun Kumar Penthi, Aditi Chatterjee, Chandrakanta Sahoo, Shanti Gopal Patra, Viswanathan Arun Nagaraj and Tabrez Khan,  Org. Chem. Front. 2025, 12, 706-716.
  2. Thermal vs. Visible-Light Photoredox-Catalyzed Cascade Radical Cyclization Involving SO2 Fixation to Access 6-Alkylsulfonylmethyl Phenanthridines  Tonish Kumar Sahu, Abhaykumar Vishwakarma, Vidyanshu Kumar, Rahimuddin Khan and Tabrez Khan,  Asian J. Org. Chem.  2024, 13, e20240002 (1-7)
  3. Total Synthesis of (-)-Magnoshinin and (+)-Merrilliaquinone: Application of a Late-Stage Oxidative Functionalization Protocol; Abdus Salam, Dileep Kumar, Tonish Kumar Sahu, Rahimuddin Khan and Tabrez Khan, Eur. J. Org. Chem. 2022 (Just Accepted) https://doi.org/10.1002/ejoc.202101452
  4. DDQ-Catalyzed Oxidative C(sp3)”H Functionalization of Aryltetralins and Subsequent Chemoselective Oxidative Demethylation to Access Dihydronaphthalenes and Dihydronaphthoquinones; Dileep Kumar, Abdus Salam, Tonish Kumar Sahu, Sujit Soumitra Sahoo and Tabrez Khan, J. Org. Chem. 2021, 86, 15096-15116.
  5. Concise and Scalable Total Syntheses of Lamellarin Z and other Natural Lamellarins; Virendra Kumar, Abdus Salam, Dileep Kumar and Tabrez Khan, ChemistrySelect 2020, 5, 14510-14514.
  6. A silica-gel accelerated [4+2] cycloaddition-based biomimetic approach towards the first total synthesis of magterpenoid C; Dileep Kumar, Virendra Kumar, Abdus Salam and Tabrez Khan, Tetrahedron Lett. 2019, 60, Article 151137
  7. Scalable Total Syntheses of some Natural and Unnatural Lamellarins: Application of a One-Pot Domino process for Regioselective Access to the Central 1,2,4-Trisubstituted Pyrrole Core; Virendra Kumar, Annapurna Awasthi, Abdus Salam and Tabrez Khan, J. Org. Chem. 2019, 84, 11596-11603.
  8. A Metal Free Domino Process for Regioselective Synthesis of 1,2,4-Trisubstituted Pyrroles: Application towards the Formal Synthesis of Ningalin B; Virendra Kumar, Annapurna Awasthi, Abhisek Metya and Tabrez Khan, J. Org. Chem. 2019, 84, 11581-11595.
  9. Total Syntheses of several Iridolactones and the Putative Structure of Noriridoid Scholarein A: An Intramolecular Pauson-Khand Reaction based One-stop Synthetic Solution; Abdus Salam, Sayan Ray, Md. Abu Zaid, Dileep Kumar and Tabrez Khan, Org. Biomol. Chem. 2019, 17, 6831-6842.
  10. A De Novo Approach for the Stereoselective Synthesis of Cyclopenta[c]pyranone Scaffold Present in Iridoids: Formal Syntheses of Isoboonein, Iridomyrmecin and Isoiridomyrmecin, Manvendra Singh Kaurav, Virendra Kumar, Dileep Kumar and Tabrez Khan, ChemistrySelect, 2018, 3, 5566-5570
  11. Synthetic studies en route to the first total synthesis of a naturally occurring quinone from Acorus gramineus, iso-merrilliaquinone, iso-magnoshininand 2-epi-3,4-dihydro magnoshinin; Dileep Kumar, Oindreela Das, Manvendra Singh Kaurav, Tabrez Khan, RSC Advances 2017, 7, 36844-36851.
  12. “An Improved Synthesis of Natural Product Inspired Chromenopyrrolizines and Chromenoindolizines Scaffolds: Rapid Access to the Diverse Pyrrolizine Analogs of Aza-Medicarpin and Tetracyclic Isolamellarin Core through a General Base and Metal free Strategy” Tabrez Khan, Virendra Kumar, Oindreela Das, Bull. Chem. Soc. Jpn. 2016, 89, 1331.
  13. “Total Synthesis and Structural Revision of Antibiotic CJ-16,264” K. C. Nicolaou, Akshay A. Shah, Henry Korman, Tabrez Khan, Lei Shi, Wisuttaya Worawalai, Emmanuel A. Theodorakis, Angew.Chem. Int. Ed. 2015, 54,9203 “9208
  14. Model studies toward a synthesis of asperaculin A: exploration of iterative intramolecular Pauson”Khand reaction based strategies to access the dioxa[5.5.5.6]fenestrane framework”; Goverdhan Mehta, Tabrez Babu Khan, Tetrahedron Letters, 2012, 53, 4558-4561.
  15. “(1-S,6-S,8-S,9-R)-9–Bromo-12–oxaspiro-[1,3-dioxolane-2,4–tricyclo[6.3.1.01,6]- dodecane]”; Goverdhan Mehta, Tabrez Babu Khan, Acta Crystallogr., Sect. E: Struct. Rep. Online, 2012, E68, o2411-o2412.
  16. “A biomimetic total synthesis of allomicrophyllone: protective Diels”Alder reaction as a stratagem”; Goverdhan Mehta, Tabrez Babu Khan, Tetrahedron Letters, 2010, 51, 6590-6593.
  17. “Total synthesis of the fungal metabolite (±)-acremine G: acceleration of a biomimetic Diels”Alder reaction on silica gel”; Goverdhan Mehta, Tabrez Babu Khan, Y.C. Sunil Kumar, Tetrahedron Letters, 2010, 51, 5116-5119.
  18. “Total syntheses of the fungal metabolites (±)-acremines A, B and I”; Goverdhan Mehta, Y.C. Sunil Kumar, Tabrez Babu Khan, Tetrahedron Letters, 2010, 51, 5112- 5115.
  19. “Anthracene-tethered aminomethyl oxadiazole chemosensor: a probe offering selective chromo- and fluorogenic signaling for targeting Cu(II)”; Sabir H. Mashraqui, Tabrez Khan, Mukesh Chandiramani, Rupesh Betkar and Kiran Poonia, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2010, 67, 361-367.
  20. “Rhodamine”Pyridyl Probe: A Selective Optical Reporter for Biologically Important Zn2+, Sabir H. Mashraqui, Tabrez Khan, Subramanian Sundaram, Rupesh Betkar and Mukesh Chandiramani, Chemistry Letters, 2009, 38, 730-731.
  21. “Phenothiazine-pyridyl chalcone: A new easily accessible colorimetric and fluorimetric “on-off ” dual sensing probe for Cu2+”, Sabir H. Mashraqui, Tabrez Khan, Subramanian Sundaram, and Shailesh Ghadigaonkar, Tetrahedron Letters, 2008, 49, 3739-3743.
  22. “New PCT probes featuring N-phenylmonoaza-18-crown-6 and aryl/pyridyloxadiazoles: Optical Spectral Studies of Solvent effects and selected metal ions”;Sabir H. Mashraqui, Subramanian Sundaram, Tabrez Khan, Shailesh Ghadigaonkar and Kirandevi Poonia, Journal of Inclusion Phenomenon & Macrocyclic Chemistry, 2008, 62, 81-90.
  23. “A new intramolecular charge transfer receptor as a selective ratiometric “off-on” sensor for Zn2+”, Sabir H. Mashraqui, Tabrez Khan, Subramanian Sundaram, Rupesh Betkar and Mukesh Chandiramani, Tetrahedron Letters, 2007, 48, 8487- 8490.
  24. “Zn2+ selective luminescent “off-on” probes derived from diaryl oxadiazole and aza- 15-crown-5″; Sabir H. Mashraqui, Subramanian Sundaram, Tabrez Khan and A. C. Bhasikuttan, Tetrahedron, 2007, 63, 11093-11100.
  25. “Benzimidazole-Chalcone: A Selective Intramolecular Charge-transfer Probe for Biologically Important Zinc Ions”, Sabir H. Mashraqui, Subramanian Sundaram and Tabrez Khan, Chemistry Letters, 2006, 35, 786-787.
  26. Aza-crown ether tethered with benzothiazole: Synthesis and optical spectral studies”, S. H. Mashraqui, V. Dhaval, S. Sundaram and T. B. Khan, Indian J. Chem., Sect B  2006, 45B, 815-819. 
  1. Tabrez Khan, Virendra Kumar & Oindreela Das, “A Rapid Access to the Diverse Pyrrolizine Analogs of Aza-Medicarpin and Tetracyclic Isolamellarin Core through a General Base and Metal free Strategy” (ICOS-21), Dec 2017, IIT Bombay, India
  2. Tabrez Khan & Oindreela Das, “Synthetic Studies towards some natural product with potent cytotoxicity towards HCC cells” First International Conference on Nutraceuticals & Chronic Diseases (INCD-2016), Sept. 2016, Kerala, India
  3. Goverdhan Mehta & Tabrez Khan, “Biomimetically Inspired First Total Synthesis of Allomicrophyllone”, 6th Junior National Organic Symposium trust Conference (J- NOST), 2011, Hyderabad, India.
  4. Goverdhan Mehta, Sunil Kumar Y. C., Tabrez Khan, “Total Syntheses of Acremine A, B, I & G”, 5th Junior National Organic Symposium trust Conference (J-NOST), 2009, Kanpur, India.
  • Associate Professor- School of Basic Sciences, IIT Bhubaneswar, Oct 2022- Present
  • Assistant Professor- School of Basic Sciences, IIT Bhubaneswar, April 2014- Oct. 2022
  • Research Investigator- Medicinal Chemistry at BBRC (Biocon-BMS R&D Centre, Syngene Intl. Ltd), Bangalore,  India, Sept. 2013- April 2014.
  • Postdoctoral Researcher with Prof. K. C. Nicolaou at The Scripps Research Institute, CA, USA, 2012-2013.
  • Postdoctoral Researcher with Prof. Goverdhan Mehta at Hyderabad Central University, India, 2010-2012.
  • Postdoctoral Researcher with Prof. Goverdhan Mehta at Indian Institute of Science, Bangalore, India, 2009-2010.
  • Research Associate at GlaxoSmithKline Pharmaceuticals, Maharashtra, India, 2008-2009.
  • Doctoral Research at University of Mumbai with Prof. S. H. Mashraqui, Maharashtra, India, 2003-2008
Scroll to Top
Skip to content